Abstract
Merino Walk virus (MWV), a proposed novel tentative species of the family Arenaviridae, was isolated from a rodent, Myotomys unisulcatus, collected at Merino Walk, Eastern Cape, South Africa, in 1985. Full-length genomic sequence confirmed MWV as an arenavirus related distantly to Mobala, Mopeia and Ippy viruses, all members of the Old World arenavirus complex. We propose MWV as a tentative novel species in the Lassa-lymphocytic choriomeningitis virus complex, based on its isolation from a novel rodent species and its genetic and serological characteristics.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Animals, Newborn
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Arenaviridae Infections / veterinary*
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Arenaviridae Infections / virology
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Arenaviruses, Old World / classification*
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Arenaviruses, Old World / isolation & purification
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Arenaviruses, Old World / pathogenicity*
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Base Sequence
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Chlorocebus aethiops
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Cluster Analysis
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Genome, Viral*
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Mice
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Mice, Inbred ICR
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Molecular Sequence Data
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Murinae / virology*
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Nucleic Acid Conformation
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Phylogeny
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RNA, Viral / genetics*
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Sequence Analysis, DNA
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Sequence Homology
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South Africa
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Vero Cells
Associated data
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GENBANK/GU078660
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GENBANK/GU078661