Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors

Angew Chem Int Ed Engl. 2010 Feb 8;49(7):1234-7. doi: 10.1002/anie.200905096.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalytic Domain
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / chemistry*
  • Glucosyltransferases / antagonists & inhibitors*
  • Glucosyltransferases / metabolism
  • Kinetics
  • Protein Structure, Tertiary
  • Trehalose / chemistry
  • Uridine Diphosphate / chemistry

Substances

  • Enzyme Inhibitors
  • Uridine Diphosphate
  • Trehalose
  • Glucosyltransferases
  • trehalose-6-phosphate synthase