Abstract
A 52-year-old man developed transient, migratory polyarthralgias in the presence of hearing loss. He then developed persistent leukocytosis and thrombocytosis. His initial transient, bilateral visual obscurations happened in context with bilateral disk edema and an enlarged blind spot. Visual symptoms progressed to vision loss and multiple branch retinal artery occlusions. It was not until later in the disease progression that gastrointestinal symptoms occurred. Electron microscopy of duodenal biopsies confirmed a diagnosis of Whipple disease.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Arthralgia / diagnosis*
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Arthralgia / drug therapy
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Arthralgia / microbiology
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Eye Infections, Bacterial / diagnosis*
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Eye Infections, Bacterial / drug therapy
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Eye Infections, Bacterial / microbiology
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Hearing Loss / diagnosis*
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Hearing Loss / drug therapy
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Hearing Loss / microbiology
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Humans
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Leukocytosis
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Macrophages / microbiology
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Male
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Middle Aged
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Retinal Artery Occlusion / diagnosis*
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Retinal Artery Occlusion / drug therapy
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Retinal Artery Occlusion / microbiology
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Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
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Tropheryma / isolation & purification
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Whipple Disease / diagnosis*
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Whipple Disease / drug therapy
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Whipple Disease / microbiology
Substances
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Trimethoprim, Sulfamethoxazole Drug Combination