Advances in sonographic detection of ovarian cancer: depiction of tumor neovascularity with microbubbles

AJR Am J Roentgenol. 2010 Feb;194(2):343-8. doi: 10.2214/AJR.09.3446.

Abstract

Objective: The purpose of this article is to discuss and illustrate the use of contrast-enhanced transvaginal sonography for the early detection of ovarian cancer and suggest how this technique may best be used to distinguish benign from malignant ovarian masses.

Conclusion: Microbubble-enhanced transvaginal sonography can enhance the evaluation of ovarian masses by early detection of tumor microvascularity.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Contrast Media
  • Female
  • Fluorocarbons*
  • Humans
  • Imaging, Three-Dimensional
  • Neovascularization, Pathologic / diagnostic imaging*
  • Ovarian Neoplasms / diagnostic imaging*
  • Phospholipids*
  • Sensitivity and Specificity
  • Sulfur Hexafluoride*
  • Ultrasonography, Doppler / methods*

Substances

  • Contrast Media
  • Fluorocarbons
  • Phospholipids
  • contrast agent BR1
  • Sulfur Hexafluoride
  • perflutren