The modern investigation and management of gastro-oesophageal reflux disease (GORD)

Clin Med (Lond). 2009 Dec;9(6):600-4. doi: 10.7861/clinmedicine.9-6-600.

Abstract

Gastro-oesophageal reflux disease results from impaired function of the LOS and acid clearance of the distal oesophagus. Most patients do not require investigation and respond either to lifestyle changes, antacid/alginates, H2A, PPI or a combination of these treatments. Surgery is only rarely indicated.

Publication types

  • Review

MeSH terms

  • Antacids / therapeutic use*
  • Deglutition / physiology*
  • Endoscopy, Gastrointestinal / methods*
  • Esophageal pH Monitoring
  • Esophagus / physiopathology
  • Fundoplication / methods*
  • Gastroesophageal Reflux* / diagnosis
  • Gastroesophageal Reflux* / physiopathology
  • Gastroesophageal Reflux* / therapy
  • Humans
  • Life Style*
  • Manometry
  • Pressure
  • Proton Pump Inhibitors / therapeutic use*

Substances

  • Antacids
  • Proton Pump Inhibitors