Short-term visual outcomes of Boston type 1 keratoprosthesis implantation

Ophthalmology. 2010 Apr;117(4):687-92. doi: 10.1016/j.ophtha.2009.09.024. Epub 2010 Jan 22.

Abstract

Purpose: To report the short-term visual outcomes after keratoprosthesis implantation.

Design: Retrospective multi center case series (Wilmer Eye Institute and University of Rochester Eye Institute).

Participants: One hundred twenty-two patients (126 eyes) with corneal diseases that were deemed ineligible to receive donor corneal transplants.

Intervention: Patients underwent a Boston type I keratoprosthesis procedure for visual rehabilitation.

Main outcome measures: The medical records of the patients were reviewed to assess intraoperative and postoperative complications, uncorrected and best-corrected visual acuity, as well as the degree of refractive error at various time points.

Results: One hundred four patients (82.5%) achieved improved vision within 6 months after surgery. An overwhelming majority of those patients who had improved vision had a manifest refraction of plano. The mean spherical refractive error was -0.57 diopters (D) and mean astigmatism was 0.10 D. Cumulatively, 7.1% patients achieved their best-corrected vision at 1 day, 24.6% at 1 week, and 70.6% at 3 months. The patients who achieved their best-corrected visual acuity after the first 3-month period most often were the ones who required multiple surgeries owing to preexisting or postoperative complications.

Conclusions: Boston keratoprosthesis seems to provide rapid visual recovery with excellent uncorrected acuity in the early postoperative period.

Financial disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Artificial Organs*
  • Child
  • Child, Preschool
  • Cornea*
  • Corneal Diseases / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Intraoperative Complications
  • Male
  • Middle Aged
  • Postoperative Complications
  • Prostheses and Implants*
  • Refractive Errors / physiopathology
  • Retrospective Studies
  • Treatment Outcome
  • Vision Disorders / rehabilitation*
  • Visual Acuity / physiology*
  • Young Adult