Periocular ulcerative dermatitis associated with gentamicin ointment prophylaxis in newborns

J Pediatr. 2010 Feb;156(2):320-1. doi: 10.1016/j.jpeds.2009.11.060.

Abstract

A recent shortage of erythromycin ointment has resulted in the use of alternative agents for newborn ocular infection prophylaxis in the United States. We report a series of 26 newborns in whom a characteristic periocular ulcerative dermatitis developed after gentamicin ointment administration at 2 Philadelphia hospitals.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Administration, Topical
  • Anti-Bacterial Agents / adverse effects*
  • Antibiotic Prophylaxis / adverse effects*
  • Drug Eruptions / etiology
  • Eyelid Diseases / chemically induced*
  • Facial Dermatoses / chemically induced*
  • Female
  • Gentamicins / adverse effects*
  • Humans
  • Infant, Newborn
  • Male
  • Ointments
  • Philadelphia

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Ointments