Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms

N Engl J Med. 2010 Jan 28;362(4):369-70. doi: 10.1056/NEJMc0910063.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Cell Transformation, Neoplastic / genetics
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Janus Kinase 2 / genetics
  • Leukemia / genetics*
  • Mutation*
  • Myeloproliferative Disorders / genetics*

Substances

  • IDH2 protein, human
  • Isocitrate Dehydrogenase
  • IDH1 protein, human
  • JAK2 protein, human
  • Janus Kinase 2