Hb F-Zhejiang: a Hb F variant due to a novel Ggamma mutation [Ggamma101(G3)Glu-->Gln, GAG>CAG] detected in a Chinese newborn

Hemoglobin. 2010;34(1):107-9. doi: 10.3109/03630260903554381.

Abstract

A G>C substitution at position 479 of the (G)gamma-globin gene results in a glutamic acid to glutamine substitution at codon 101 of the (G)gamma-globin chain, a new gamma chain variant that we have named Hb F-Zhejiang [(G)gamma101(G3)Glu-->Gln].

Publication types

  • Case Reports

MeSH terms

  • Amino Acid Substitution / genetics*
  • China
  • Female
  • Fetal Hemoglobin / genetics*
  • Genetic Variation / genetics*
  • Humans
  • Infant, Newborn
  • Point Mutation*
  • gamma-Globins / genetics*

Substances

  • gamma-Globins
  • Fetal Hemoglobin