[Analysis of clinical course of severe acute biliary and non biliary pancreatitis: a comparative study]

Orv Hetil. 2010 Feb 14;151(7):265-8. doi: 10.1556/OH.2010.28760.
[Article in Hungarian]

Abstract

The acute pancreatitis is a relative common disease with incidence of 5-80 per 100000 people of the population. The number of new cases has steadily increased in recent years. The two main etiological factors are alcohol and cholelithiasis. The incidence of alcoholic pancreatitis is higher in male, and the incidence of gallstone pancreatitis is higher in female.

Aim: To summarize the difference between the clinical course of biliary and not biliary type of severe acute pancreatitis by analyzing the data of these patients.

Methods: 139 patients treated with severe acute pancreatitis were divided in two groups: biliary (A group) and non biliary (B group) of origin. The two groups were compared on the basis of sex and age, mortality, morbidity, number of surgery and hospital stay. chi 2 probe was used for the statistical analysis.

Results: The complications in biliary group were more serious. The average mortality rate was 15.1%, 17.8% in group A and 13.8% in group B. The mortality rate of female patients in group A was significantly higher.

Conclusion: Female patients suffering from severe biliary acute pancreatitis have higher morbidity and mortality rate. Therefore an elective cholecystectomy is suggested in old female patients with serious co-morbidity and gallstones, before any complications.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • APACHE
  • Adult
  • Age Factors
  • Aged
  • Biliary Tract Diseases / complications
  • Cholelithiasis / complications*
  • Digestive System Surgical Procedures
  • Female
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Pancreatitis, Acute Necrotizing / complications
  • Pancreatitis, Acute Necrotizing / etiology*
  • Pancreatitis, Acute Necrotizing / mortality
  • Pancreatitis, Acute Necrotizing / physiopathology
  • Pancreatitis, Acute Necrotizing / surgery*
  • Risk Factors
  • Severity of Illness Index
  • Sex Factors