A novel two-step kit for topical treatment of tinea pedis--an open study

J Eur Acad Dermatol Venereol. 2010 Sep;24(9):1099-101. doi: 10.1111/j.1468-3083.2010.03576.x. Epub 2010 Feb 2.

Abstract

Background: Tinea pedis is a common skin disease affecting most of the population during their lifetime. Topical and systemic treatments give only temporary relief.

Objective: To evaluate the efficacy and safety of a new topical treatment for moderate-to-severe tinea pedis.

Methods: Fifty patients suffering from tinea pedis were treated in two stages: the active stage--single use of the novel topical solution for 45 min and novel cream twice weekly for 4 weeks; the preventive stage--cream application once weekly for 10 months.

Results: Forty-five patients completed the active stage and achieved 76% cure rate. The medication was well tolerated; one patient dropped from the study because of very mild irritation. No other topical or systemic side effects were noted. Another five patients were lost to follow-up during the preventive stage. The total cure rate after the preventive stage was 70%.

Conclusions: This novel treatment was found to be effective, well tolerated and safe in the treatment of moderate and severe tinea pedis during the active and the preventive stages.

MeSH terms

  • Administration, Topical
  • Adult
  • Antifungal Agents / therapeutic use*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tinea Pedis / drug therapy*

Substances

  • Antifungal Agents