Fabrication of Ag@SiO(2)@Y(2)O(3):Er nanostructures for bioimaging: tuning of the upconversion fluorescence with silver nanoparticles

J Am Chem Soc. 2010 Mar 10;132(9):2850-1. doi: 10.1021/ja909108x.

Abstract

We demonstrated that the nanostructures comprising silver cores and dense layers of Y(2)O(3):Er separated by a silica shell are an excellent model system to study the interaction between upconversion materials and metals in nanoscale. This architecture allows for versatile control of the Y(2)O(3):Er-metal interaction through control of the silica dielectric spacer thickness and the metal-core size. Finally, the nanoparticles are potentially interesting as fluorescent labels in, for instance (single particle), imaging experiments or bioassays which require low background or tissue penetrating wavelengths.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Cell Line, Tumor
  • Europium / chemistry*
  • Fluorescence
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry
  • Fluorescent Dyes / pharmacokinetics*
  • Humans
  • Luminescent Measurements
  • Male
  • Materials Testing
  • Molecular Imaging / methods*
  • Nanostructures / chemistry*
  • Particle Size
  • Prostatic Neoplasms / diagnosis
  • Silicon Dioxide / chemistry*
  • Silver / chemistry*
  • Surface Properties
  • Tissue Distribution
  • Yttrium / chemistry*

Substances

  • Fluorescent Dyes
  • Silver
  • Europium
  • Yttrium
  • Silicon Dioxide
  • yttria