Genetics of obsessive-compulsive disorder

Psychiatr Clin North Am. 2010 Mar;33(1):141-58. doi: 10.1016/j.psc.2009.11.001.

Abstract

Obsessive-compulsive disorder is a common debilitating condition affecting individuals from childhood through adult life. There is good evidence of genetic contribution to its etiology, but environmental risk factors also are likely to be involved. The condition probably has a complex pattern of inheritance. Molecular studies have identified several potentially relevant genes, but much additional research is needed to establish definitive causes of the condition.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Environment
  • Genetic Association Studies
  • Genetic Linkage
  • Humans
  • Obsessive-Compulsive Disorder / epidemiology
  • Obsessive-Compulsive Disorder / genetics*
  • Phenotype