The assessment of the filtering bleb function with anterior segment optical coherence tomography

J Glaucoma. 2010 Oct-Nov;19(8):551-5. doi: 10.1097/IJG.0b013e3181ca76f3.

Abstract

Purpose: To assess the usefulness of anterior segment optical coherence tomography (AS-OCT) in evaluating postoperative filtering bleb function.

Methods: Forty-eight eyes of 39 patients who had earlier undergone trabeculectomy were enrolled. Blebs were imaged with a commercially available AS-OCT system. The correlation between intraocular pressure (IOP) and 4 quantitative parameters, bleb height, bleb wall thickness, and the height and extent of internal cavity, and 2 qualitative parameters, bleb wall reflectivity, and the presence or absence of posterior episcleral fluid, were analyzed.

Results: Of the 39 participants, 25 (64.1%) were males (mean age, 65.3±10.0 y). The height and extent of the internal cavity and the bleb height were not correlated with the IOP. The bleb wall thickness was negatively (P=0.004) correlated with the IOP. The mean IOP in eyes with a low-reflectivity bleb wall was significantly (P=0.001) lower than in eyes with a high-reflectivity wall. The IOP levels were significantly (P=0.008) lower in eyes with posterior episcleral fluid than in eyes without it.

Conclusions: AS-OCT is a useful tool to evaluate filtering bleb function. The height and extent of the total bleb and the internal cavity were not correlated with IOP control. A low-reflectivity wall and the presence of episcleral fluid were associated with lower IOP.

MeSH terms

  • Aged
  • Anterior Eye Segment / physiopathology*
  • Blister / physiopathology*
  • Female
  • Glaucoma / surgery*
  • Humans
  • Intraocular Pressure / physiology
  • Male
  • Postoperative Period
  • Surgical Flaps
  • Tomography, Optical Coherence*
  • Trabeculectomy*