Clickable bifunctional radiometal chelates for peptide labeling

Chem Commun (Camb). 2010 Mar 14;46(10):1706-8. doi: 10.1039/b924784j. Epub 2010 Feb 6.

Abstract

Novel synthetic methods for producing an array of chelates for use in "click"-radiolabeling of peptides are described, and their reactivity with regards to subsequent conjugation and radiolabeling is discussed.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Chelating Agents / chemical synthesis
  • Chelating Agents / chemistry*
  • Cross-Linking Reagents / chemical synthesis
  • Cross-Linking Reagents / chemistry*
  • Isotope Labeling / methods*
  • Metals / chemistry*
  • Models, Molecular
  • Molecular Conformation
  • Peptides / chemistry*
  • Quantum Theory

Substances

  • Chelating Agents
  • Cross-Linking Reagents
  • Metals
  • Peptides