Abstract
Asphorodin (1), a new diglycoside, has been isolated from the ethyl acetate-soluble fraction of Asphodelus tenuifolius. It showed significant inhibitory activity against the enzyme lipoxygenase in a concentration-dependent manner. The Lineweaver-Burk and Dixon plots indicated that the nature of inhibition was non-competitive.
MeSH terms
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Dose-Response Relationship, Drug
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology*
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Liliaceae / chemistry*
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Lipoxygenase Inhibitors / chemistry
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Lipoxygenase Inhibitors / isolation & purification*
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Lipoxygenase Inhibitors / pharmacology*
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Molecular Structure
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Pakistan
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Triterpenes / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology*
Substances
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Glycosides
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Lipoxygenase Inhibitors
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Triterpenes
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asphorodin