Steroids and alkaloids from the South China Sea sponge Axinella sp

Shu-Hua Qi; Yi-Fei Wang; Si Zhang

doi:10.1080/10286020903367136

Steroids and alkaloids from the South China Sea sponge Axinella sp

J Asian Nat Prod Res. 2009 Dec;11(12):1040-4. doi: 10.1080/10286020903367136.

Authors

Shu-Hua Qi¹, Yi-Fei Wang, Si Zhang

Affiliation

¹ Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, Guangzhou, China. [email protected]

PMID: 20183274
DOI: 10.1080/10286020903367136

Abstract

A new steroid 24beta-methylcholasta-1,8,14,22,25-penten-3-one-5alpha-ol (1) and a new alkaloid 1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane (2), together with four known compounds, were isolated from the EtOH extract of the South China Sea sponge Axinella sp. The structures of 1 and 2 were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR spectral data.

MeSH terms

Animals
Axinella / chemistry*
Cholestenones / chemistry
Cholestenones / isolation & purification*
Indole Alkaloids / chemistry
Indole Alkaloids / isolation & purification*
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Stereoisomerism
Steroids / chemistry
Steroids / isolation & purification*

Substances

1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane
Cholestenones
Indole Alkaloids
Steroids