Diffusion-weighted MRI evaluation of breast cancer extension

Clin Imaging. 2010 Mar-Apr;34(2):89-96. doi: 10.1016/j.clinimag.2009.09.002.

Abstract

Aim: To investigate the feasibility of using diffusion-weighted MR imaging (DWI) to accurately measure breast cancer extension.

Materials and methods: The extensions of 59 breast lesions were investigated on DW images and apparent diffusion coefficient (ADC) maps and compared to the pathological exams.

Results: Three groups were observed: accurate, overdiagnosis, and false negative. There were no significant differences seen in accurate or false-negative group when b was 500 and 1000 s/mm(2) when two lesions in the overdiagnosis group at both b values.

Conclusion: DWI and the ADC value have potential for evaluating cancer extension.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / pathology*
  • Diffusion Magnetic Resonance Imaging / methods*
  • Feasibility Studies
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Middle Aged
  • Neoplasm Invasiveness
  • Reproducibility of Results
  • Sensitivity and Specificity