Three cases of Moraxella osloensis meningitis: a difficult experience in species identification and determination of clinical significance

J Korean Med Sci. 2010 Mar;25(3):501-4. doi: 10.3346/jkms.2010.25.3.501. Epub 2010 Feb 17.

Abstract

We had three cases of Moraxella osloensis meningitis. The species identification was impossible by conventional and commercial phenotypic tests. However, we could identify the species using the 16S rRNA gene sequencing. Determination of clinical significance was difficult in one patient. All three patients recovered by appropriate antimicrobial therapy.

Keywords: 16S Ribosomal RNA Gene Sequencing; Meningitis; Moraxella osloensis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Typing Techniques*
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Meningitis, Bacterial / drug therapy
  • Meningitis, Bacterial / microbiology*
  • Moraxella / pathogenicity*
  • Moraxellaceae Infections / drug therapy
  • Moraxellaceae Infections / microbiology*
  • RNA, Bacterial / analysis
  • RNA, Ribosomal, 16S / analysis

Substances

  • Anti-Bacterial Agents
  • RNA, Bacterial
  • RNA, Ribosomal, 16S