Detecting bacterial growth in continuous ambulatory peritoneal dialysis effluent using two culture methods

Korean J Intern Med. 2010 Mar;25(1):82-5. doi: 10.3904/kjim.2010.25.1.82. Epub 2010 Feb 26.

Abstract

Background/aims: The aim of this study was to evaluate the peritonitis-causing bacteria detected in peritoneal fluid using a blood culture bottle in patients undergoing continuous ambulatory peritoneal dialysis (CAPD).

Methods: One-hundred and eleven dialysates from 43 patients suspected of peritonitis related to CAPD were retrospectively evaluated between May 2000 and February 2008. In all cases, 5 to 10 mL of dialysate was inoculated into a pair of BacT/Alert blood culture bottles, and 50 mL of centrifuged dialysate was simultaneously inoculated into a solid culture media for conventional culture. The results were compared to those of the conventional culture method. Isolated microorganisms were compared between the two methods.

Results: The blood culture method was positive in 78.6% (88 / 112) of dialysate specimens and the conventional culture method in 50% (56 / 112, p < 0.001).

Conclusions: The blood culture method using the BacT/Alert system is useful for culturing dialysates and improves the positive culture rate in patients with suspected peritonitis compared to the conventional culture method.

Keywords: Culture media; Peritoneal dialysis; Peritonitis; Sensitivity and specificity.

Publication types

  • Comparative Study

MeSH terms

  • Culture Media
  • Dialysis Solutions
  • Gram-Negative Bacterial Infections / diagnosis*
  • Gram-Negative Bacterial Infections / microbiology
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / microbiology
  • Humans
  • Kidney Failure, Chronic / therapy*
  • Microbiological Techniques / methods*
  • Peritoneal Dialysis, Continuous Ambulatory / adverse effects*
  • Peritonitis / diagnosis*
  • Peritonitis / microbiology
  • Sensitivity and Specificity

Substances

  • Culture Media
  • Dialysis Solutions