Head and neck sarcoma: report of a case treated by intensity-modulated radiation therapy

Int J Clin Oncol. 2010 Jun;15(3):305-9. doi: 10.1007/s10147-010-0037-x. Epub 2010 Mar 2.

Abstract

We report on a 71-year-old woman with parapharyngeal sarcoma. Surgery could not be performed because of the size and location of the tumor. After failure of four cycles of chemotherapy, intensity-modulated radiation therapy (IMRT) achieved complete clinical response and partial magnetic resonance imaging response (80%) at 24 months of follow-up. The results of radiotherapy, especially IMRT, for nonresectable head and neck soft tissue sarcoma are discussed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibiotics, Antineoplastic / therapeutic use
  • Dose Fractionation, Radiation
  • Doxorubicin / therapeutic use
  • Female
  • Head and Neck Neoplasms / drug therapy
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / radiotherapy*
  • Humans
  • Magnetic Resonance Imaging
  • Pharynx
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy, Intensity-Modulated*
  • Sarcoma / drug therapy
  • Sarcoma / pathology
  • Sarcoma / radiotherapy*
  • Tomography, X-Ray Computed
  • Treatment Failure

Substances

  • Antibiotics, Antineoplastic
  • Doxorubicin