Abstract
Transmissible proventriculitis associated with infectious bronchitis virus (IBV) was at first seen in eastern China in mid-1995, and is now endemic in China. Herein, the complete genome sequence of a proventiculitis-associated infectious bronchitis coronavirus (ZJ971) was sequenced and analyzed. Compared with the genome of the vaccine strain H120, ZJ971 had 54 nucleotide substitutions and a deletion in the 3'-UTR. The substitutions were in the regions of nsp2-nsp5, nsp7, nsp12, nsp13, nsp15, S and N genes, and the untranslating region. The results indicated that ZJ971 could be a variant of IBV strain H120.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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3' Untranslated Regions
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Animals
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China / epidemiology
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Coronavirus Infections / epidemiology
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Coronavirus Infections / veterinary*
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Coronavirus Infections / virology
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Genome, Viral*
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Infectious bronchitis virus / genetics*
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Infectious bronchitis virus / isolation & purification*
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Point Mutation
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Proventriculus / pathology
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Proventriculus / virology*
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Sequence Analysis, DNA*
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Sequence Homology
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Stomach Diseases / epidemiology
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Stomach Diseases / veterinary*
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Stomach Diseases / virology
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Viral Proteins / genetics
Substances
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3' Untranslated Regions
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Viral Proteins