D3 receptor target engagement in humans with ABT-925 using [11C](+)-PHNO PET

Int J Neuropsychopharmacol. 2010 Apr;13(3):291-2. doi: 10.1017/S1461145710000180. Epub 2010 Mar 3.

Authors

Mark Day¹, Earle Bain, Gerard Marek, Mario Saltarelli, Gerard B Fox

Affiliation

¹ Global Pharmaceutical Research and Development, Translational Neuroimaging, Abbott, Abbott Park, IL60064, USA. [email protected]

PMID: 20196920
DOI: 10.1017/S1461145710000180

No abstract available

MeSH terms

Brain / diagnostic imaging*
Brain / drug effects
Humans
Oxazines / pharmacokinetics*
Positron-Emission Tomography / methods*
Receptors, Dopamine D3 / antagonists & inhibitors*
Receptors, Dopamine D3 / metabolism*

Substances

Oxazines
Receptors, Dopamine D3
naxagolide