Ignoring lack of association of heart rate variability with cardiovascular disease and risk factors: response to the manuscript "The relationship of autonomic imbalance, heart rate variability cardiovascular disease risk factors" by Julian F. Thayer, Shelby S. Yamamoto, Jos F. Brosschot

A Kluttig; O Kuss; K H Greiser

doi:10.1016/j.ijcard.2010.02.048

Ignoring lack of association of heart rate variability with cardiovascular disease and risk factors: response to the manuscript "The relationship of autonomic imbalance, heart rate variability cardiovascular disease risk factors" by Julian F. Thayer, Shelby S. Yamamoto, Jos F. Brosschot

Int J Cardiol. 2010 Nov 19;145(2):375-376. doi: 10.1016/j.ijcard.2010.02.048. Epub 2010 Mar 5.

Authors

A Kluttig¹, O Kuss², K H Greiser³

Affiliations

¹ Institute of Medical Epidemiology, Biostatistics, and Informatics, University of Halle-Wittenberg, Halle (Saale), Germany. Electronic address: [email protected].
² Institute of Medical Epidemiology, Biostatistics, and Informatics, University of Halle-Wittenberg, Halle (Saale), Germany.
³ Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

PMID: 20207033
DOI: 10.1016/j.ijcard.2010.02.048

Abstract

A reduced heart rate variability (HRV) is a marker of autonomic dysfunction and has been shown to be associated with an increased risk of cardiovascular morbidity and mortality. However, especially regarding the association of HRV with cardiovascular risk factors the literature is rather inconsistent. We therefore critically discuss the review of Thayer et al. concerning the relationship between autonomic imbalance, heart rate variability and cardiovascular disease risk factors.

Publication types

Comment
Letter

MeSH terms

Autonomic Nervous System / physiopathology*
Cardiovascular Diseases / physiopathology*
Heart Rate / physiology*
Humans
Risk Factors