Cadherin-based adhesion is a potential target for niche manipulation to protect hematopoietic stem cells in adult bone marrow

Cell Stem Cell. 2010 Mar 5;6(3):194-8. doi: 10.1016/j.stem.2009.04.013.

Authors

Kentaro Hosokawa¹, Fumio Arai, Hiroki Yoshihara, Hiroko Iwasaki, Mark Hembree, Tong Yin, Yuka Nakamura, Yumiko Gomei, Keiyo Takubo, Haruko Shiama, Sahoko Matsuoka, Linheng Li, Toshio Suda

Affiliation

¹ Department of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology, School of Medicine, Keio University, 35 Shinano-machi, Shinjuku-ku, Tokyo, 160-8582, Japan.

PMID: 20207221
DOI: 10.1016/j.stem.2009.04.013

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aging*
Animals
Bone Marrow / metabolism*
Cadherins / genetics
Cadherins / metabolism*
Cell Adhesion
Cell Communication
Gene Expression Regulation
Hematopoietic Stem Cells / cytology*
Hematopoietic Stem Cells / metabolism*
Mice
Stem Cell Niche / cytology*
Stem Cell Niche / metabolism*
Stress, Physiological

Substances

Cadherins