Advanced contrast modalities for X-ray radiology: Phase-contrast and dark-field imaging using a grating interferometer

Z Med Phys. 2010;20(1):7-16. doi: 10.1016/j.zemedi.2009.11.003. Epub 2010 Jan 15.

Abstract

Here we review our recent progress in the field of X-ray dark-field and phase-contrast imaging using a grating interferometer. We describe the basic imaging principles of grating-based phase-contrast and dark-field radiography and present some exemplary results obtained for simple test objects and biological specimens. Furthermore, we discuss how phase-contrast and dark-field radiography can be combined with the concept of computed tomography, and yield highly detailed three-dimensional insights into biomedical sample. Exemplary results obtained with standard X-ray tube sources and highly brilliant synchrotron sources are presented.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / diagnostic imaging
  • Chickens
  • Diagnostic Imaging / methods
  • Formaldehyde
  • Heart / diagnostic imaging
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Interferometry / instrumentation
  • Interferometry / methods*
  • Microscopy, Phase-Contrast / methods
  • Postmortem Changes
  • Radiographic Image Interpretation, Computer-Assisted / methods
  • Radiology / standards*
  • Rats
  • Synchrotrons
  • X-Rays

Substances

  • Formaldehyde