Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)

Pharmacogenet Genomics. 2011 Mar;21(3):152-61. doi: 10.1097/FPC.0b013e3283385a1c.

Authors

Laura M Hodges¹, Svetlana M Markova, Leslie W Chinn, Jason M Gow, Deanna L Kroetz, Teri E Klein, Russ B Altman

Affiliation

¹ Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

No abstract available

Publication types

Research Support, N.I.H., Extramural

MeSH terms

ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1 / chemistry
ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics*
ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism*
Adenosine Triphosphate / metabolism
Anticonvulsants / pharmacokinetics
Anticonvulsants / therapeutic use
Antineoplastic Agents / pharmacokinetics
Antineoplastic Agents / therapeutic use
Disease / genetics*
Drug Resistance / genetics*
Drug Resistance, Neoplasm / genetics
Humans
Mutation
Pharmacogenetics
Substrate Specificity
Tissue Distribution

Substances

ABCB1 protein, human
ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1
Anticonvulsants
Antineoplastic Agents
Adenosine Triphosphate

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