First case of human "Candidatus Neoehrlichia mikurensis" infection in a febrile patient with chronic lymphocytic leukemia

Christina Welinder-Olsson; Eva Kjellin; Krista Vaht; Stefan Jacobsson; Christine Wennerås

doi:10.1128/JCM.02423-09

First case of human "Candidatus Neoehrlichia mikurensis" infection in a febrile patient with chronic lymphocytic leukemia

J Clin Microbiol. 2010 May;48(5):1956-9. doi: 10.1128/JCM.02423-09. Epub 2010 Mar 10.

Authors

Christina Welinder-Olsson¹, Eva Kjellin, Krista Vaht, Stefan Jacobsson, Christine Wennerås

Affiliation

¹ Department of Clinical Bacteriology, Sahlgrenska University Hospital, Guldhedsgatan 10, Box 7193, 402 34 Gothenburg, Sweden.

Abstract

An immunocompromised patient presented with febrile episodes, an erysipelas-like rash, and thromboembolic complications. Amplification of 16S rRNA gene sequences from blood and sequence analysis revealed "Candidatus Neoehrlichia mikurensis." We report the first case of human disease caused by "Ca. Neoehrlichia mikurensis."

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Anaplasmataceae / classification
Anaplasmataceae / genetics
Anaplasmataceae / isolation & purification*
Anaplasmataceae Infections / diagnosis*
Anaplasmataceae Infections / microbiology
Anaplasmataceae Infections / pathology
Blood / microbiology
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
Humans
Immunocompromised Host
Leukemia, Lymphocytic, Chronic, B-Cell / complications*
Male
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA
Thromboembolism / microbiology
Thromboembolism / pathology

Substances

DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S