Double (V27A/S31N) mutant 2009 pandemic influenza A (H1N1) virus isolated from adamantane non-treated inmunocompetent child

Andrés Antón; María Angeles Marcos; Miguel Julián Martínez; Susana Ramón; Ricard Isanta; Patricia de Molina; María Teresa Jiménez de Anta; Tomàs Pumarola

doi:10.1016/j.diagmicrobio.2009.12.019

Double (V27A/S31N) mutant 2009 pandemic influenza A (H1N1) virus isolated from adamantane non-treated inmunocompetent child

Diagn Microbiol Infect Dis. 2010 May;67(1):114-5. doi: 10.1016/j.diagmicrobio.2009.12.019. Epub 2010 Mar 12.

Authors

Andrés Antón¹, María Angeles Marcos, Miguel Julián Martínez, Susana Ramón, Ricard Isanta, Patricia de Molina, María Teresa Jiménez de Anta, Tomàs Pumarola

Affiliation

¹ Laboratori de Microbiologia, Hospital Clínic, 08036, Barcelona, Spain. [email protected]

PMID: 20227229
DOI: 10.1016/j.diagmicrobio.2009.12.019

Abstract

We report the first strain of 2009 pandemic influenza A (H1N1) virus with V27A mutation in addition to S31N substitution in M2 gen. It was isolated from adamantane non-treated child.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adamantane / therapeutic use*
Adolescent
Amino Acid Substitution / genetics*
Antiviral Agents / therapeutic use*
Female
Humans
Influenza A Virus, H1N1 Subtype / genetics*
Influenza A Virus, H1N1 Subtype / isolation & purification
Influenza, Human / virology*
Mutation, Missense*
Spain
Viral Matrix Proteins / genetics

Substances

Antiviral Agents
M2 protein, Influenza A virus
Viral Matrix Proteins
Adamantane