Sequential therapy of primary cardiac lymphoma with cardiectomy, total artificial heart support, and cardiac transplantation

J Heart Lung Transplant. 2010 Jun;29(6):707-9. doi: 10.1016/j.healun.2010.01.014. Epub 2010 Mar 15.

Abstract

Primary cardiac T-cell lymphoma is an extremely rare entity, with only 3 patients having been reported so far in the literature. We describe the case of a young patient with acute heart failure involving the whole myocardium. The patient successfully underwent emergency cardiectomy, custom-made total artificial heart implantation and heart transplantation, combined with chemotherapy. The problems we encountered with this rare disease are discussed and compared with those of previous studies.

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols
  • Cardiac Surgical Procedures*
  • Cyclophosphamide
  • Doxorubicin
  • Female
  • Heart Neoplasms / pathology
  • Heart Neoplasms / surgery*
  • Heart Transplantation*
  • Heart, Artificial*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lymphoma / pathology
  • Lymphoma / surgery*
  • Myocardium / pathology
  • Prednisone
  • Vincristine
  • Young Adult

Substances

  • Immunosuppressive Agents
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CHOP protocol