Abstract
The homeobox gene (Hoxa13) codes for a transcription factor protein that binds to AT-rich DNA sequences and controls expression of many important proteins during embryonic morphogenesis. We report complete backbone NMR chemical shift assignments of mouse Hoxa13 DNA binding domain bound to an 11-residue DNA duplex (BMRB no. 16577).
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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DNA / chemistry*
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DNA / metabolism
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Homeodomain Proteins / chemistry*
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Homeodomain Proteins / genetics
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Homeodomain Proteins / metabolism
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Mice
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Molecular Sequence Data
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Nuclear Magnetic Resonance, Biomolecular
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Protein Structure, Secondary
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Protein Structure, Tertiary
Substances
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Homeodomain Proteins
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homeobox protein HOXA13
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DNA