Conservative management is associated with a decreased risk of definitive stoma after anastomotic leakage complicating sphincter-saving resection for rectal cancer

Colorectal Dis. 2011 Jun;13(6):632-7. doi: 10.1111/j.1463-1318.2010.02252.x. Epub 2010 Mar 10.

Abstract

Aim: Anastomotic leakage (AL) after sphincter-saving resection (SSR) for rectal cancer can result in a definitive stoma (DS). The aim of the study was to assess risk factors for DS after AL-complicating SSR.

Method: Between 1997 and 2007, 200 patients underwent SSR for rectal cancer. AL occurred in 20.5% (41/200) [symptomatic 13.5% (n = 27), asymptomatic 7% (n = 14)]. Possible risk factors for DS after AL were analysed.

Results: Management of AL consisted in no treatment (n = 14), medical treatment (n = 6), local drainage (n = 10) and abdominal reoperation (n = 11). After a median follow-up of 38 months, the overall rate of DS was 3% (n = 6): 0% for asymptomatic vs 22% after symptomatic AL (P = 0.061). After reoperation, the risk of DS was 13% when the anastomosis was preserved vs 100% after Hartmann's procedure (P = 0.007). Risk factors of DS after AL included obesity, age over 65, American Society of Anesthesiologists (ASA) score > 2 and abdominal reoperation for AL.

Conclusion: The risk of DS after SSR for cancer is low (3%) but rises to 22% after symptomatic AL. This risk depends on the surgical treatment for AL and is up to 100% if a Hartmann's procedure is performed.

MeSH terms

  • Age Factors
  • Aged
  • Anal Canal / surgery
  • Anastomosis, Surgical / adverse effects
  • Anastomotic Leak / etiology
  • Anastomotic Leak / pathology
  • Anastomotic Leak / therapy*
  • Body Mass Index
  • Digestive System Surgical Procedures / adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / surgery*
  • Rectum / surgery*
  • Reoperation
  • Retrospective Studies
  • Risk Factors
  • Surgical Stomas*