[MRI in diagnosis and follow-up of patients with adult metabolic disease: contribution of new techniques]

Rev Neurol (Paris). 2011 Mar;167(3):216-20. doi: 10.1016/j.neurol.2010.01.013. Epub 2010 Mar 24.
[Article in French]

Abstract

Introduction: Conventional MRI allows diagnostic and prognosis approaches for patients with suspected metabolic disease.

Background: Bilateral and symmetrical abnormalities are the most suggestive aspects. Signal characteristics (intensity, difference of signal on various sequences), lesion extension and location provide important etiological information. Non-conventional MRI techniques are particularly interesting for pathophysiology. Different MRI modalities offer promising techniques for monitoring treatments and patient follow-up.

Conclusion: Combining different MRI modalities can contribute to the diagnosis and help improve understanding of the pathogenic mechanisms of adult metabolic diseases; they offer promising options for the prognosis and treatment follow-up.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Brain / metabolism
  • Brain / pathology*
  • Brain Chemistry
  • Brain Diseases, Metabolic / metabolism
  • Brain Diseases, Metabolic / pathology*
  • Brain Diseases, Metabolic / therapy
  • Brain Ischemia / pathology
  • Dementia, Vascular / pathology
  • Follow-Up Studies
  • Humans
  • Leukodystrophy, Metachromatic / pathology
  • Leukoencephalopathies / metabolism
  • Leukoencephalopathies / pathology*
  • Leukoencephalopathies / therapy
  • Magnetic Resonance Imaging* / methods
  • Magnetic Resonance Spectroscopy
  • Prognosis