Bilateral endophthalmitis as a primary manifestation of Streptococcus dysgalactiae endocarditis and the role of 16S rDNA polymerase chain reaction in identification

Nimal Wickramasinghe; Kathryn Harris

doi:10.1016/j.diagmicrobio.2010.01.008

Bilateral endophthalmitis as a primary manifestation of Streptococcus dysgalactiae endocarditis and the role of 16S rDNA polymerase chain reaction in identification

Diagn Microbiol Infect Dis. 2010 Jun;67(2):185-7. doi: 10.1016/j.diagmicrobio.2010.01.008. Epub 2010 Mar 24.

Authors

Nimal Wickramasinghe¹, Kathryn Harris

Affiliation

¹ Department of Microbiology, University Hospital of Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX West Midlands, UK.

PMID: 20338706
DOI: 10.1016/j.diagmicrobio.2010.01.008

Abstract

Bilateral endogenous endophthalmitis is a rare complication of endocarditis. We present the case of a 72-year-old female who presented with heart failure and bilateral endogenous endophthalmitis. Endocarditis was confirmed on transesophageal echocardiography. All cultures were negative, but 16S rDNA sequencing on vitreal aspirates identified Streptococcus dysgalactiae as the likely pathogen.

Publication types

Case Reports

MeSH terms

Aged
Bacteriological Techniques / methods*
DNA, Bacterial / genetics
DNA, Ribosomal / genetics
Echocardiography, Transesophageal
Endocarditis, Bacterial / complications*
Endocarditis, Bacterial / diagnosis
Endocarditis, Bacterial / microbiology*
Endophthalmitis / microbiology*
Female
Humans
Polymerase Chain Reaction / methods*
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA
Streptococcal Infections / diagnosis*
Streptococcal Infections / microbiology
Streptococcus / isolation & purification*

Substances

DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S