Vectorization of copper complexes via biocompatible and biodegradable PLGA nanoparticles

Nanotechnology. 2010 Apr 23;21(16):165101. doi: 10.1088/0957-4484/21/16/165101. Epub 2010 Mar 26.

Abstract

A double emulsion-solvent diffusion approach with fully biocompatible materials was used to encapsulate copper complexes within biodegradable nanoparticles, for which the release kinetics profiles have highlighted their potential use for a prolonged circulating administration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorbable Implants*
  • Biocompatible Materials / chemistry*
  • Copper / chemistry*
  • Diffusion
  • Drug Implants / chemistry*
  • Kinetics
  • Lactic Acid / chemistry*
  • Materials Testing
  • Nanoparticles / chemistry*
  • Nanoparticles / ultrastructure
  • Particle Size
  • Polyglycolic Acid / chemistry*
  • Polylactic Acid-Polyglycolic Acid Copolymer
  • Surface Properties

Substances

  • Biocompatible Materials
  • Drug Implants
  • Polylactic Acid-Polyglycolic Acid Copolymer
  • Polyglycolic Acid
  • Lactic Acid
  • Copper