Isolation and identification of the antibacterial active compound from petroleum ether extract of neem oil

Yu-Qun Zhang; Jiao Xu; Zhong-Qiong Yin; Ren-Yong Jia; Yang Lu; Fan Yang; Yong-Hua Du; Ping Zou; Cheng Lv; Ting-Xiu Hu; Shu-Liang Liu; Gang Shu; Geng Yi

doi:10.1016/j.fitote.2010.03.015

Isolation and identification of the antibacterial active compound from petroleum ether extract of neem oil

Fitoterapia. 2010 Oct;81(7):747-50. doi: 10.1016/j.fitote.2010.03.015. Epub 2010 Mar 31.

Authors

Yu-Qun Zhang¹, Jiao Xu, Zhong-Qiong Yin, Ren-Yong Jia, Yang Lu, Fan Yang, Yong-Hua Du, Ping Zou, Cheng Lv, Ting-Xiu Hu, Shu-Liang Liu, Gang Shu, Geng Yi

Affiliation

¹ College of Animal Medicine, Sichuan Agricultural University, Ya'an, 625014, PR China.

PMID: 20362038
DOI: 10.1016/j.fitote.2010.03.015

Abstract

From a petroleum ether extract of neem oil (Azadirachta indica A. Juss) the new tetrahydrofuranyl diester 1 was isolated as an anti-bacterial constituent. 1 showed significant activities against three standard bacterial strains, including Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922 and Salmonella enteritidis CMCC (B) 50041.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / isolation & purification*
Anti-Bacterial Agents / pharmacology
Azadirachta / chemistry*
Escherichia coli / drug effects*
Furans / isolation & purification*
Furans / pharmacology
Glycerides / chemistry
Glycerides / pharmacology*
Plant Oils / chemistry
Plant Oils / pharmacology*
Salmonella enteritidis / drug effects*
Seeds
Staphylococcus aureus / drug effects*
Stearic Acids / isolation & purification*
Stearic Acids / pharmacology
Terpenes / chemistry
Terpenes / pharmacology*

Substances

Anti-Bacterial Agents
Furans
Glycerides
Plant Oils
Stearic Acids
Terpenes
m-octadecanoic acid-3,4-tetrahydrofuran diester
neem oil