[Treatment of childhood dystonia]

Arch Pediatr. 2010 May;17(5):540-53. doi: 10.1016/j.arcped.2010.02.016. Epub 2010 Apr 1.
[Article in French]

Abstract

Dystonia is not uncommon in childhood, but is clinically very heterogeneous. Therefore, introduction and follow-up of the treatment of dystonia in children are often a challenge for the physicians. Progresses in functional neurosurgery have open new fields in the treatment of dystonia in children, but it should be managed by a multidisciplinary team. This paper reviews the various therapeutic options available for childhood-onset dystonia, with a specific attention to dosage and side effects of the drugs regarding pediatric population according to the data of the literature. The rational strategy for therapeutic management of the various types of childhood dystonia is discussed.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Algorithms
  • Anticonvulsants / therapeutic use
  • Benzodiazepines / therapeutic use
  • Botulinum Toxins, Type A / therapeutic use
  • Child
  • Cholinergic Antagonists / therapeutic use
  • Cooperative Behavior
  • Dantrolene / therapeutic use
  • Deep Brain Stimulation
  • Dopamine Agents / therapeutic use
  • Dystonic Disorders / etiology
  • Dystonic Disorders / therapy*
  • Humans
  • Interdisciplinary Communication
  • Levodopa / therapeutic use
  • Muscle Relaxants, Central / therapeutic use
  • Patient Care Team
  • Prognosis

Substances

  • Anticonvulsants
  • Cholinergic Antagonists
  • Dopamine Agents
  • Muscle Relaxants, Central
  • Benzodiazepines
  • Levodopa
  • Botulinum Toxins, Type A
  • Dantrolene