Visualizing blood cell emergence from aortic endothelium

Gemma Swiers; Nancy A Speck; Marella F T R de Bruijn

doi:10.1016/j.stem.2010.03.007

Visualizing blood cell emergence from aortic endothelium

Cell Stem Cell. 2010 Apr 2;6(4):289-290. doi: 10.1016/j.stem.2010.03.007.

Authors

Gemma Swiers¹, Nancy A Speck², Marella F T R de Bruijn³

Affiliations

¹ MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.
² Abramson Family Cancer Research Institute and Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: [email protected].
³ MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK. Electronic address: [email protected].

PMID: 20362528
DOI: 10.1016/j.stem.2010.03.007

Abstract

Three recent Nature papers use time-lapse confocal imaging to visualize the birth of blood cells from the aortic endothelium. Two studies (Bertrand et al., 2010; Kissa and Herbomel, 2010) utilize the zebrafish embryo, while the third (Boisset et al., 2010) develops a novel technique to image the mouse aorta.

Grants and funding

R01 CA058343/CA/NCI NIH HHS/United States