Cycling toward elimination of leukemic stem cells

Daniel Goff; Catriona Jamieson

doi:10.1016/j.stem.2010.03.008

Cycling toward elimination of leukemic stem cells

Cell Stem Cell. 2010 Apr 2;6(4):296-297. doi: 10.1016/j.stem.2010.03.008.

Authors

Daniel Goff¹, Catriona Jamieson²

Affiliations

¹ Department of Medicine and Moores Cancer Center, University of California at San Diego, San Diego, CA 92093, USA.
² Department of Medicine and Moores Cancer Center, University of California at San Diego, San Diego, CA 92093, USA. Electronic address: [email protected].

PMID: 20362532
DOI: 10.1016/j.stem.2010.03.008

Abstract

In two recent articles in Science Translational Medicine and Nature Biotechnology, Saito et al. (2010) identify a molecular signature of acute myeloid leukemia (AML) stem cells and demonstrate that quiescent AML stem cells become sensitized to chemotherapy after G-CSF stimulation.

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