[Effects of airborne fine particulate matters on human immunological indicators]

Wei Sheng Yan Jiu. 2010 Jan;39(1):50-2.
[Article in Chinese]

Abstract

Objective: To explore effects of airborne fine particulate matters on human immunological indicators.

Methods: All subjects were measured the level of PM2. 5 individual exposure with personal sampling devices. Serum immunological indicators, such as WBC, NE, NE%, Ly, Ly%, CD4+, CD8+, CD4+ / CD8+, IgA, IgM, IgG and IgE were detected through enzyme-linked immunosorbent assay. Then, comparing the difference of PM2.5 exposure and immunological indicators between two groups.

Results: For the level of PM2.5 daily exposure, traffic policemen (115.4 +/- 46.2) microg/m3) was significantly higher than residents ((74.9 +/- 40.1) +/- g/ m(-3)). And there was also significant difference in some immunological indicators, such as Ly%, CD4+, CD8+, IgM, IgG, IgE, CC 16 and CRP, between two groups.

Conclusion: Long-term high level of airborne fine particulate matters exposure may change some blood immunological indicators, affect the health of the immune system.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Air Pollutants / adverse effects*
  • Air Pollutants / analysis
  • China
  • Environmental Exposure / adverse effects*
  • Humans
  • Immunoglobulins / blood*
  • Male
  • Middle Aged
  • Occupational Exposure / adverse effects
  • Particulate Matter / adverse effects*
  • Particulate Matter / analysis
  • Police
  • Surveys and Questionnaires
  • Time Factors
  • Uteroglobin / blood

Substances

  • Air Pollutants
  • Immunoglobulins
  • Particulate Matter
  • SCGB1A1 protein, human
  • Uteroglobin