MRICOM-MRI COntrast Modelling using 2D T1-T2 correlation spectra and relaxation signatures

Magn Reson Imaging. 2010 Jun;28(5):661-8. doi: 10.1016/j.mri.2010.02.011. Epub 2010 Apr 8.

Abstract

Image contrast is calculated by inputting experimental 2D T(1)-T(2) relaxation spectra into the ODIN software interface. The method involves characterising a magnetic resonance imaging pulse sequence with a "relaxation signature" which describes the sensitivity of the sequence to relaxation and is independent of sample parameters. Maximising (or minimising) the overlap between the experimental 2D T(1)-T(2) relaxation spectra and the relaxation signature can then be used to maximise image contrast. The concept is illustrated using relaxation signatures for the echo planar imaging and Turbo spin-echo imaging sequences, together with in-vitro 2D T(1)-T(2) spectra for liver and cartilage.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Echo-Planar Imaging / instrumentation
  • Echo-Planar Imaging / methods*
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Phantoms, Imaging
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Statistics as Topic