Topography of the masseter muscle in relation to treatment with botulinum toxin type A

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Aug;110(2):167-71. doi: 10.1016/j.tripleo.2009.12.036. Epub 2010 Apr 9.

Abstract

Objective: The objective of this study was to provide the safest and most efficient site for injection of botulinum toxin type A into the masseter muscle.

Study design: This study was performed on 40 hemifaces from cadavers. The surface of the masseter was compartmentalized into areas I to VIII. Areas I, III, V, and VII were assigned to represent the upper 4 compartments from the posterior aspect of each muscle, and areas II, IV, VI, and VIII were assigned to represent the lower 4 compartments.

Results: The parotid gland usually covered compartments I and II, and the marginal mandibular branch of the facial nerve was located a mean of 7.4 mm above the inferior mandibular margin. The parotid duct was usually located above the reference line connecting the tragus and the cheilion.

Conclusion: The center of compartment VI is the safest and most efficient injection site for botulinum toxin type A into the masseter muscle.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Botulinum Toxins, Type A / administration & dosage*
  • Cadaver
  • Female
  • Humans
  • Injections, Intramuscular / methods
  • Male
  • Mandibular Nerve / anatomy & histology
  • Masseter Muscle / anatomy & histology*
  • Masseter Muscle / blood supply
  • Masseter Muscle / innervation
  • Middle Aged
  • Neuromuscular Agents / administration & dosage*
  • Parotid Gland / anatomy & histology
  • Safety

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A