Rapid access to 1-methyleneindenes via palladium-catalyzed tandem reactions of 1-(2,2-dibromovinyl)-2-alkynylbenzenes with arylboronic acids

Chem Commun (Camb). 2010 May 7;46(17):2950-2. doi: 10.1039/b926763h. Epub 2010 Mar 8.

Abstract

A novel and efficient route for the synthesis of 1-methyleneindenes via palladium-catalyzed tandem reactions of 1-(2,2-dibromovinyl)-2-alkynylbenzene with arylboronic acids is described. This reaction proceeded under mild conditions with high efficiency and excellent selectivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry
  • Benzene / chemistry*
  • Boronic Acids / chemistry*
  • Catalysis
  • Indenes / chemical synthesis
  • Indenes / chemistry*
  • Palladium / chemistry*

Substances

  • Alkynes
  • Boronic Acids
  • Indenes
  • Palladium
  • Benzene