[Detection of contralateral axillary sentinel lymph node by lymphoscintigraphy in breast cancer: prognostic implications]

Rev Esp Med Nucl. 2010 May-Jun;29(3):135-7. doi: 10.1016/j.remn.2009.12.007. Epub 2010 Apr 15.
[Article in Spanish]

Abstract

The role of nuclear medicine in the detection of sentinel lymph nodes (SLNs) in primary breast cancer is very useful to determine regional lymphatic drainage from the affected breast, mainly its anatomical and/or tumoral individual variability and to determine the initial tumor stage. We present the case of an infiltrating ductal carcinoma of the breast (T2) in the junction of the inner quadrants of the right breast studied by lymphoscintigraphy and gamma probe detection. Three non-metastatic sentinel lymph nodes were found with the selective lymphadenectomy: two in the ipsilateral axilla and one in the contralateral axilla. The lymphoscintigraphic finding of the axillary sentinel lymph node contralateral to the affected breast demonstrates the individual anatomical variability in mammary drainage. It emphasizes the importance of nuclear medicine imaging techniques in its detection and generates new prognostic approaches with impact on therapeutic measures and patient follow-up.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Axilla
  • Breast / anatomy & histology
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Carcinoma, Ductal, Breast / diagnostic imaging
  • Carcinoma, Ductal, Breast / secondary*
  • Carcinoma, Ductal, Breast / surgery
  • Female
  • Humans
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Lymphatic System / anatomy & histology
  • Mastectomy, Segmental
  • Prognosis
  • Radiology, Interventional
  • Radionuclide Imaging
  • Radiopharmaceuticals / administration & dosage
  • Sentinel Lymph Node Biopsy* / methods
  • Technetium Tc 99m Aggregated Albumin / administration & dosage

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Aggregated Albumin
  • technetium Tc 99m nanocolloid