[Human lung cancer: role of TLR7 and TLR8 in cell survival and chemoresistance]

Med Sci (Paris). 2010 Apr;26(4):435-7. doi: 10.1051/medsci/2010264435.
[Article in French]
No abstract available

Publication types

  • News

MeSH terms

  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / metabolism*
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Cell Line, Tumor / cytology
  • Cell Survival
  • Drug Resistance, Neoplasm / drug effects
  • Drug Resistance, Neoplasm / physiology
  • Gene Expression Regulation, Neoplastic / drug effects
  • Genes, bcl-2 / drug effects
  • Guanosine / analogs & derivatives
  • Guanosine / pharmacology
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / metabolism*
  • Lung Neoplasms / pathology
  • NF-kappa B / metabolism
  • Neoplasm Proteins / physiology*
  • Proto-Oncogene Proteins c-bcl-2 / biosynthesis
  • Receptors, CCR4 / biosynthesis
  • Receptors, CCR4 / genetics
  • Toll-Like Receptor 7 / agonists
  • Toll-Like Receptor 7 / physiology*
  • Toll-Like Receptor 8 / agonists
  • Toll-Like Receptor 8 / physiology*
  • Tumor Stem Cell Assay

Substances

  • Antineoplastic Agents
  • CCR4 protein, human
  • NF-kappa B
  • Neoplasm Proteins
  • Proto-Oncogene Proteins c-bcl-2
  • Receptors, CCR4
  • TLR7 protein, human
  • TLR8 protein, human
  • Toll-Like Receptor 7
  • Toll-Like Receptor 8
  • Guanosine
  • loxoribine