The potential of backscattering interferometry as an in vitro clinical diagnostic tool for the serological diagnosis of infectious disease

Analyst. 2010 Jul;135(7):1535-7. doi: 10.1039/c0an00098a. Epub 2010 Apr 22.

Abstract

Backscattering interferometry enables the detection of syphilis antibody-antigen interactions in the presence of human serum, showing promise as a diagnostic tool for the serological diagnosis of infectious disease with potentially quantitative capabilities.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibodies / blood
  • Antibodies / immunology
  • Antigens / blood
  • Antigens / immunology
  • Humans
  • Immunoglobulin G / metabolism
  • Interferometry / methods*
  • Light
  • Syphilis / blood
  • Syphilis / diagnosis*
  • Syphilis Serodiagnosis / methods*

Substances

  • Antibodies
  • Antigens
  • Immunoglobulin G