Evaluation of a preventive program to reduce sensitization at a beryllium metal, oxide, and alloy production plant

J Occup Environ Med. 2010 May;52(5):505-12. doi: 10.1097/JOM.0b013e3181d6c338.

Abstract

Objective: We evaluated a workplace preventive program's effectiveness, which emphasized skin and respiratory protection, workplace cleanliness, and beryllium migration control in lowering beryllium sensitization.

Methods: We compared sensitization prevalence and incidence rates for workers hired before and after the program using available cross sectional and longitudinal surveillance data.

Results: Sensitization prevalence was 8.9% for the Pre-Program Group and 2.1% for the Program Group. The sensitization incidence rate was 3.7/1000 person-months for the Pre-Program Group and 1.7/1000 person-months for the Program Group. After making adjustments for potential selection and information bias, sensitization prevalence for the Pre-Program Group was 3.8 times higher (95% CI = 1.5 to 9.3) than the Program Group. The sensitization incidence rate ratio comparing the Pre-Program Group to the Program Group was 1.6 (95% CI = 0.8 to 3.6).

Conclusions: This preventive program reduced the prevalence of but did not eliminate beryllium sensitization.

Publication types

  • Evaluation Study

MeSH terms

  • Alloys*
  • Beryllium / adverse effects*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Industry*
  • Male
  • Occupational Exposure / prevention & control*
  • Oxides*

Substances

  • Alloys
  • Oxides
  • Beryllium