New tricks for old biomarkers: thymidylate synthase expression as a predictor of pemetrexed activity in malignant mesothelioma

Ann Oncol. 2010 Jul;21(7):1560-1561. doi: 10.1093/annonc/mdq253. Epub 2010 May 5.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Biomarkers, Tumor / metabolism*
  • Glutamates / therapeutic use*
  • Guanine / analogs & derivatives*
  • Guanine / therapeutic use
  • Humans
  • Mesothelioma / diagnosis
  • Mesothelioma / drug therapy
  • Mesothelioma / metabolism*
  • Pemetrexed
  • Pleural Neoplasms / diagnosis
  • Pleural Neoplasms / drug therapy
  • Pleural Neoplasms / metabolism*
  • Survival Rate
  • Thymidylate Synthase / antagonists & inhibitors*
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • Glutamates
  • Pemetrexed
  • Guanine
  • Thymidylate Synthase