Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells

Cell Stem Cell. 2010 May 7;6(5):407-11. doi: 10.1016/j.stem.2010.04.005.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line
  • Embryonic Stem Cells / metabolism*
  • Epigenesis, Genetic
  • Fragile X Mental Retardation Protein / genetics
  • Fragile X Mental Retardation Protein / metabolism
  • Fragile X Syndrome / metabolism*
  • Fragile X Syndrome / pathology
  • Gene Expression Regulation, Developmental
  • Humans
  • Induced Pluripotent Stem Cells / metabolism*
  • Models, Biological*

Substances

  • FMR1 protein, human
  • Fragile X Mental Retardation Protein