Abstract
Three new dibenzocyclooctadiene lignans, schilancifolignans A-C (1-3), together with thirteen known ones, were isolated from the leaves and stems of Schisandra lancifolia. The structures of 1-3 were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compounds 1-3 were tested for their anti-human immunodeficiency virus-1 activities and showed weak bioactivities.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-HIV Agents / chemistry*
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Anti-HIV Agents / isolation & purification
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Anti-HIV Agents / pharmacology*
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Cyclooctanes / chemistry*
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Cyclooctanes / isolation & purification
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Cyclooctanes / pharmacology*
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HIV-1 / drug effects*
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Humans
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Lignans / chemistry*
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Lignans / isolation & purification
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Lignans / pharmacology*
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Plant Components, Aerial / chemistry
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Schisandra / chemistry*
Substances
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Anti-HIV Agents
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Cyclooctanes
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Lignans
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dibenzocyclooctadiene lignan